(Bundy 2011) alludes to a deadlock that is preventing the wider adoption of theorem provers by the mathematical community: On the one hand, the mathematicians need to use the proof assistants to build a large formal library of mathematical results.
As inactives selected from PubChem database much more resembles the second part of the study (various-test sets mode) – the chemical space of inactive molecules is much more limited comparing to ZINC database or any other commercially available library of compounds, results obtained for this external validation sets coincide with those obtained in the various-test set mode.
But, on the other hand, they do not want to use the provers since there is no such library of previously proved results they can build upon.
To validate whether sequence variations identified by these methods provide reliable information about mutations in the whole library, the results of screening of five genes (total length of 3.5 kb) were compared with the results of HRM analysis (Table 5).
Screening of tissue-specific cDNA library and results of Relative RT-PCR indicate that the relationship between genotype, (i.e., dynamic network of genes and their protein regulatory elements) and phenotype is non-bijective, and mendelian inheritance is a special case only.
Screening of a small library of CABA molecules resulted in the identification of four compounds that measurably inhibited AfRio1 activity.
The sequencing of the normalized cDNA library of Pachycara brachycephalum resulted in 481,802 reads with an average read length of 321 bases (Table 1).
Finally, one article was added via citation chasing and one from the library of a reviewer, resulting in a total of 29 articles.
In order to discover active compounds with inhibitory activity against methicillin-resistant S. aureus pyruvate kinase (MRSA-PK), screening of an extract library of marine invertebrates resulted in the identification of bis-indole alkaloids from the Topsentia pachastrelloides.
Underestimation of library concentration results in multiple library molecules associating with the same bead within an emulsion microdroplet or overlapping images of DNA clusters after bridge PCR.
