Sentence examples for libraries of variants from inspiring English sources

Affibody binding proteins are selected from phage-displayed libraries of variants of the 58 residue Z domain.

As a result, directed evolution remains a valuable tool for synthetic biology, enabling the identification of desired functionalities from large libraries of variants.

Rational design, usually guided by computational prediction, and selection from libraries of variants of natural proteins have been used with success in the engineering of novel non-natural receptors.

Libraries of variants were constructed and screened on sucrose, allowing the identification of a mutant that showed a 6-fold enhanced activity toward sucrose compared to the wild-type enzyme.

Directed evolution, a process which mimics Darwinian selection on a laboratory scale, has allowed significant strides to be made in the field of synthetic biology by allowing rapid identification of desired properties from large libraries of variants.

This enabled us to construct large libraries of variants in one reaction, deliver multiple corresponding sgRNAs and donor templates en masse to yeast cells, and identify those that stimulate a certain cell behavior by next-generation sequencing," said Postdoctoral Fellow Xiaoge Guo, Ph.D., one of the study's first authors.

Increasingly, combinatorial approaches are being taken to select 'fit' sequences from libraries of variant proteins.

Expression libraries of variant serpins could be rapidly probed with proteases to develop novel inhibitors if optimal systems were available.

High-throughput selection methods can allow large libraries of variant aldolases to be evaluated.

However, we hoped to identify a more dramatic difference in order to facilitate future screening of libraries of variant TEs.

Phage display allows high-throughput screening of libraries of variant nucleotide sequences with diversity up to 10 to 10 [ 11, 42, 49].