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A further refinement of the concept of drug-likeness is required for compound libraries intended for central nervous system (CNS) targets to account for the limitations imposed by blood brain barrier permeability.
Here we report a protocol, Mab-seq, that generates genome-scale quality evaluations for nucleic acid libraries intended for deep-sequencing.
Total RNA from each tissue/condition was used as the source of starting material for cDNA synthesis and production of normalized cDNA libraries intended for 454 sequencing.
In addition, libraries intended for drug discovery utility need to further adhere to a restricted range of physicochemical properties necessary for both parenteral or oral bioavailability and, perhaps, central nervous system penetration [23,24].
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The library libhepml is a C++ library intended for parsing and serialization of HepML tags, and representing the HepML block in computer memory.
Cornell may have been the first American university library intended for extensive use by undergraduates as well as by the faculty.
Newlib is a "C library intended for use on embedded systems". It has the advantage of not having so much cruft as Glibc at the obvious cost of incomplete support (and idiosyncratic behavior) in the fringes.
Matthias Schulz In addition to advanced training for musicians, the Lyceum project has also focused on a media library intended for students and public that would improve unrestricted access to books and scores.
It is part of ArgKit, a Java library intended for building custom software based on argumentation.
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