As R-loop formation is a transcription-related phenomenon, is highly expressed genes more liable to form R-loops with their transcripts?
Partially unfolded proteins have exposed hydrophobic surfaces and are liable to form aggregates. Molecular chaperones bind to the exposed surfaces and an attempt is made to refold the protein.
The direct apposition of the posterior surface of this muscle to the anterior aspect of the head and neck of the femur is of great advantage, two moving surfaces are very much less liable to form adhesions to one another than are two surfaces in more or less constant apposition, such as would be true of the capsule and of the underlying joint surface.
Interestingly, we have shown that two pathogenic α-synuclein mutants, A30P and A53T, which are liable to form fibrils or oligomers in vitro, inhibited proteasome activity more strongly than did wild-type α-synuclein, while Δ73-83 Δ73-83 and β-synuclein, neither of which assemutantnto filandnts in vitro, did not inhibit proteasome activity.
Microscopic and spectroscopic investigations in the electron microscope and synchrotron radiation experiments suggest that Zn ions are transported through these channels in a liable (yet unidentified) form, and then form stable complexes upon His binding.
Trusts are liable to one form of inheritance tax: every 10 years, HM Revenue and Customs is entitled to claim 6% of the value of the trust fund.
What has the atomic number of 16, and is liable, in the form of a compound, to be spritzed into the stratosphere by the mega-ton?
However, if they meet in the δ- to δ- orientation, a potential cation channel is formed as in Fig 3a, whereas, if they meet side-on as in Fig 3c, a proton or water channel is liable to be formed.
Like all young players, his form is liable to wax and wane but on Wednesday his maturity was startling.
His analysis of the mixed constitution, which had enabled Rome to avoid the cycle of change and deterioration to which simple constitutional forms were liable, is full of problems, but it has exercised widespread influence, from Cicero's De republica down to Machiavelli and Montesquieu.
