Ferric iron, as stripped from Tf and Lf, is taken up by the Fbp ABC transporter system, and is thought to be the major mechanism by which iron from Tf and Lf enters the cell, while haem is transported into the cytoplasm by a different currently unknown mechanism [34].
The flip-flop between the two interfaces of the bilayer, characterized by the rate parameter lf, can take minutes, hours, 709) or days, depending on the strength of the interaction between the chemical and the headgroup region.
In mammalian cells, both iron-charged Lf (holo-Lf) and iron-lacking Lf (apo-Lf) can be taken up by the cell through the same receptor (LfR) on the cell surface.
We previously demonstrated that bovine Fe-Lf is taken up by cells residing in the lamina propria and Peyer's patches [ 36].
To determine the cellular mechanism through which B-holo-Lf is taken up and internalized by both variants of amoebae, we used several types of inhibitors of endocytosis pathways, and B-holo-Lf internalization was evaluated by flow cytometry).
The latter corroborates earlier findings by Fischer et al. (2010) that MC-LF is taken up more rapidly or efficiently by OATP1B family members than are other MC congeners.
LF: I've been taking street photos of Dublin and #Dublinfaces for a couple of years now and to me the character of the city is in the back alleys and streets behind the main streets and etched into the faces of its inhabitants.
Then by taking the constructed LF metamodel as a prior-knowledge and mapping the output space of the LF metamodel to that of the studied high-fidelity (HF) model, a variable fidelity (VF) metamodel is created to approximate the relationships between the design variables and corresponding output responses.
The two alleles at each locus can take Lf different possible allelic states.
Others think that most of the work done by LFs could be done by taking a notion of surface syntax seriously, not positing hidden structure, and running very complicated semantic theories to account for the data.
