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LF is commonly measured by means of the International Electrotechnical Commission (IEC) flickermeter [2] that, for historical reasons, was designed and tested only with reference to voltage amplitude modulation (AM), which was the first source of LF identified and referring only to 60-W incandescent bulbs, which were the most diffused lamps all over the word at that time.
Initial experiments using affinity isolation by Lf identified a 98-kDa lactoferrin-binding protein named LbpA, formerly known as IroA [ 46].
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Other QTLs for LF were identified on chromosomes 1, 2, 3, and 11.
The most significant QTLs for LF were identified in the same location on chromosome 5 in both populations.
B, T and Natural killer (NK) cells containing high levels of Lf were identified in 4T1 tumors, suggesting they had migrated from the intestine.
This causes the early-time linear flow data points on RTA plot to be scattered, and therefore m LF cannot be identified very accurately.
The main advantage of pressure buildup test data analysis is that the flow rate is constant during the test (Q = 0); therefore, the data points are significantly less scattered compared to the data on RTA plots, and m LF can be identified more accurately using PBA plots.
The study objectives were twofold; assess whether community-based health workers (both volunteer workers and salaried employees of the national health system) were able to accurately identify members in their communities with lymphoedema and hydrocoele, and to pilot an SMS tool for reporting these identified LF morbidity cases.
Based on the literature, no previous test has been capable of identifying LF homozygous and LF heterozygous males with this level of reliability.
Immunohistochemistry revealed estrogen receptor-β was positively stained in both male and female LF cells with similar density, while estrogen receptor-α was identified on female LF cells with lower density and was barely seen on cells from a male patient.
Using overlapping decapeptide analysis, we identified six common LF antigenic regions targeted by those individuals with moderate levels of antibodies to LF and high in vitro toxin neutralizing activity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com