Mean Pearson's coefficient of three sets of independent experiments revealed 0.933 ± 0.092 for co-localisation of p55γ and 0.741 ± 0.093 for p85α with BMPRII-LF (Additional file 1: Figure S1B).
The apoptosis cells were slightly increased from 15.98% to 21.36% after 5 days exposure to LF-MF (Additional file 1: Figure S1A and B).
After challenged with B16-F10 cells, a significant tumefaction was showed in spleen and kidney, while this abnormal tumefaction could be reversed after exposure to LF-MF (Additional file 2: Figure S2A, B and E).
Then we checked the expression of genes associated with apoptosis, Bcl2 and survivin, and found that mRNA expressions of the genes were not changed after exposure to LF-MF (Additional file 1: Figure S1C and 1D).
The masses of lung, liver, and heart were mildly altered in both normal mice and tumor-bearing mice after LF-MF exposure (Additional file 2: Figure S2C, D and F).
Because LF-A/St, LF-A and LF-A/X have the exact same N-terminal sequence while LF-HMA has two additional residues at the N-terminus (Fig. 1) but the latter has lower potency, we performed more extensive analyses of the role of the N-terminal residue, described below.
When the 2011 eruption started, JMA installed 6 additional seismometers, 3 LF microphones, 4 tiltmeters and 2 cameras to strengthen monitoring of Shinmoedake in cooperation with other organizations.
In additional, HF and LF and Others can definitely make classification accuracy over 90%%; the features were extracted from dynamically added frequency bands, such as, "level 11" if needed.
Underlined motifs exhibit tissue specificity (GC vs LF) based on our analysis (Additional file 3).
LF levels were determined in additional fluid from the patient's right pleura.
