Sentence examples for levodopa does not from inspiring English sources
Exogenous levodopa changes striatal neuronal activity and increases extracellular dopamine concentrations, and with adequate inhibition of peripheral metabolism levodopa does not change mean cerebral blood flow.
The present experiments demonstrate that levodopa does not enhance delayed retrograde degeneration of dopaminergic neurons induced by intrastriatal administration of 6-OHDA.
Oral administration of 2,000 mg/kg of layered hydroxide nanocomposite with and without levodopa does not alter the microscopic structure of the vital organs.
However, several studies have demonstrated that the extended release formulation of levodopa does not reduce "off" time compared to the immediate release formulation.
Furthermore, levodopa does not restore dysfunctional cognitive network patterns to normal as it does motor network patterns on either functional MRI (Jubault et al., 2009), or PET (Huang et al., 2007).
Levodopa did not significantly reduce striatal RAC* binding and striatal binding did not differ significantly between TS and control groups.
The expert review reported that levodopa did not accelerate PD progression and that no pharmacological intervention was neuroprotective.
The lack of effect of Order by itself (F1,38 = 2.451, p = 0.126), or Group × Order interaction (F1,38 = 1.161, p = 0.288) suggests that levodopa did not affect force decrement, or the difference between patients and control subjects.
Levodopa administration does not improve all executive deficits in PDD (Pillon et al., 1989; Poewe et al., 1991; Jubault et al., 2009), or even in early Parkinson's disease (Lewis et al., 2005; Muslimovic et al., 2005).
Dopamine agonists directly stimulate dopamine receptors and unlike levodopa their symptomatic effect does not depend on the presence of dopamine producing neurons (Junghanns et al. 2004).
More importantly levodopa, notwithstanding its symptomatic benefits, does not cure PD, nor does it halt the development of additional features during the course of PD, such as autonomic dysfunction, gait disturbance, freezing and dementia (Olanow et al. 2004).
