For our model, the myosin pair consisted of either two identical myosin dimers with lever arm stiffness k F. Each myosin dimer has two motor domains (gray sandals), and each myosin pair is linked through their centers of mass by a linear spring k s.
The displacement ratio between the input and output motions of one of the levers, plus the stiffness at either end of this lever are obtained based on the analysis.
Long constructs have increased lever arm and stiffness; thus, they increase the stress on the terminal screws and may result in junctional kyphosis [ 23].
Theoretical analysis reveals that the lever's compliance, the contact stiffness, and the load mass have significant influence on the static and dynamic performances of the system.
Experimental results show that the modeling accuracy is significantly improved if the influence of the lever's compliance, the contact stiffness, and the load mass is taken into consideration.
The circular torsion bar is fixed in plate B and supported but free to rotate in plate A. A load applied at point C on the lever twists the bar, and the stiffness of the suspension, which depends on the length and diameter of the bar and the length of the lever, can be easily varied by changing L.
A lever-type damper has lower strength and stiffness than a wedge-type damper, but these characteristics can be greatly improved by rational structural design.
The paper also has a compelling final model that simply explains the results over various conditions of the study yet assumes only a limited number of motor properties (ratio of motor stall forces, stepping rates, stiffness of intermotor linkage and motor lever arm stiffness).
In this paper, the equivalent structure shown in Figure 4(b) is proposed to account for the lever's compliance, where klever is the equivalent lateral stiffness of the lever with "clamped-free" boundary conditions.
Estimate inter-molecular tension per step (∆T) for movement on keratocytes as a function of k F /k s —Stochastic simulations of movement of motor ensembles with lever arm flexural rigidity k F and inter-motor stiffness k s on the digitized actin network were performed in Mathematica.
