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Aggression levels were defined using standard practices, as described in Table 1[ 35] 35].
Sedentary, moderate and vigorous activity levels were defined using published cut-points: sedentary <100 counts per minute (cpm), moderate 1535 3959 cpm and vigorous ≥3960 cpm [ 27, 28].
Low RBC folate levels were defined using cutoffs of 140 ng/ml (Institute of Medicine, NIH) and 151 ng/ml (WHO technical consultation).
Severity levels were defined using a combination of contractures (0, 45, or 90 degrees) in 8 proximal interphalangeal and metacarpophalangeal joints of the index, middle, ring, and little fingers.
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Socioeconomic level was defined using a matrix that included the head of household's educational level (schooling categories) and household assets (gas-fueled water heater, computer, refrigerator, washing machine, microwave oven, and car), according to a socioeconomic classification that has been widely used and validated in Chile [ 13].
New core level probe sets were defined using most up-to-date transcript data.
Additionally, armoured layer damages on the slope were defined using a damage level parameter.
These regions were defined using multi-level modelling of PCR prevalence data and spatial and geo-climatic measures.
13 18 In these studies NK cell subpopulations were defined using the level of NKp46 expression on a per-cell basis using the mean fluorescence intensity (MFI).
Individual-level SES was defined using the three aforementioned categories of educational attainment.
The educational level of women was defined using years of schooling, and they were grouped into illiterate, primary school, secondary school, and tertiary levels of education.
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