The levels of α1(I) and α2(I) procollagen were also increased in Smad7 knock-down fibroblasts compared to control fibroblasts, although only COL1A1 levels appeared to be affected at an mRNA level.
Finally, 18S expression levels appear to be affected to a lesser extent by partial RNA degradation than are mRNA expression levels [ 8].
Serum ACE levels appear to be affected by the I/D polymorphism and are correlated with prognosis in patients with ALI/ARDS, indicating that further investigation of the clinical significance of the ACE in ARDS might be of value.
While TE is affected by both moderate and high aminotransferase levels, ARFI appears to be affected by high levels as shown in a large multicentre study [106].
Genes with expression levels greater than 1.5 times the wild type, or less than 2/3 the wild type, levels are considered to be affected by the knockout.
Triglyceride levels are known to be affected by n-3 PUFA intake.
DNA methylation levels are known to be affected by age and gender in healthy and disease conditions.
SP-A and SP-D levels were reported to be affected by PCP infection via inflammatory mediators [ 10, 11] or reported to influence on PCP infection, and to play a role in host defenses against P. jirovecii [ 30- 32].
ROS and dNTP levels are known to be affected by mitochondrial dysfunction, and thus one might also expect to see some association of these measures with the mitochondrial respiratory measures.
While MYC, P21, and AREG levels were confirmed to be affected by suppression of BRD4, we found that FAS was downregulated upon suppression of BRD2 only but not BRD4, while FGFR1 is upregulated upon suppression of either BRD3 or BRD4.
