Sentence examples for levels of the complement from inspiring English sources

Expression levels of the complement C5 (C5) and complement component C6-like (C6) genes were significantly increased between 8 h and 24 h, and 4 h to 24 h, respectively.

It has been hypothesized that high levels of the complement factor mannose-binding lectin (MBL) are associated with a favourable disease course of RA by facilitating the clearance of pathogenic immunoglobulin G (IgG) lacking galactose sugar moieties.

In both clinical and experimental studies, severe secondary insults in TBI were observed in parallel to pronounced complement activation, specifically increased levels of the complement activation product, C5b-9 [ 10].

We and others showed that serum levels of HMGB1 are elevated in SLE patients and correlate with SLE disease activity score and, inversely, with levels of the complement components C3 and C4.

Further stratification for the presence of B35 revealed that HLA-B*35 correlated with the low levels of the complement genes, with the lowest levels observed in B35-positive lcSSc-PAH samples (lcSSc PAH B35+ vs lcSSc PAH B35-, p < 0.01).

A subset of the samples from patients with SLE used in the heterotrimer assay had previously been assessed for various markers of disease activity, including patient SLE Disease Activity Index (SLEDAI) scores at the time of serum draw, erythrocyte sedimentation rate (ESR), concentrations of anti-double stranded DNA (dsDNA) antibodies, and levels of the complement components C3 and C4.

The objective of this study was to determine whether an elevated level of the complement activation fragment Bb in early pregnancy was associated with spontaneous preterm birth (SPTB) at less than 34 weeks' gestation or SPTB between 34 and 37 weeks' gestation (late SPTB).

The findings also suggest that it is important to consider variation in the levels of these complement proteins across a population when planning immunisation schedules.

For example, combined transcriptomic and proteomic analyses of synovial fluids and membranes from OA patients showed elevated levels of activation of the complement pathway, a series of proteins that have effector functions in the innate immune system (Wang et al., 2011).

Higher frequency and titers of serum autoantibodies to C1q and dsDNA and lower levels of serum of the complement components C3 and C4 were detected in patients with active SLE and active nephritis compared to patients with inactive SLE and without a renal involvement, respectively (Tables 3 and 4).

Moreover, upon comparison of the levels of the three functional complement activities between HD patients who used modified cellulose membrane (n = 35) and HD patients who used polysulfone membrane (n = 29) in the age-matched group, there were no significant differences (data not shown).