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Schools are more specialized engineering schools don't compete with music schools, for instance—and they are of varying levels of selectivity.
However, the series exhibits low levels of selectivity over PDE11, a phosphodiesterase with unknown function.
This PDE5 specificity translated to levels of selectivity over PDE6 that were hitherto unprecedented in the sildenafil scaffold.
Following the bridge year, students are directed towards one of the secondary education tracks, which are divided into three main streams with varying orientations, durations and levels of selectivity, subsequently providing access to distinct higher education opportunities.
Several aryloxyazetidines also showed high levels of selectivity, with one compound, 25, displaying promising in vivo pharmacokinetics and significantly improved aqueous solubility over related compounds containing a biaryl substituent.
These inhibitors bind the C. glabrata DHFR enzyme with subnanomolar potency, display greater than 2000-fold levels of selectivity over the human enzyme, and inhibit the growth of C. glabrata at levels observed with clinically employed therapeutics.
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A value near to 20,000 indicates a high contrast level (high degree of selectivity), and a value close to 10,000 indicates a low contrast level (poor degree of selectivity).
But look around: there are lots of schools with Penn-like characteristics but not the same level of selectivity: private urban research universities of a moderate size: George Washington, Johns Hopkins, Washington University in St . Louis Carnegie Mellon, Tufts, Vanderbilt and so on.
The nanosensor showed some level of selectivity to TNT versus other chemical molecules that had similar molecular structures.
Potent inhibitors of RON tyrosine kinase with various level of selectivity for c-Met RTK were obtained.
Out of these, the best was the double variant I80 V/V83L, which induces a relatively high level of selectivity for (R,R -2 (77 % ee).
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