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Levels of physical capability could reflect both clinically manifest and undetected disease and ageing processes.
It is difficult to extrapolate findings from these studies to other countries since absolute levels of physical capability vary between populations [ 12].
Therefore, understanding the contributors to bone health may be informative to the maintenance of good levels of physical capability in later life.
We therefore hypothesised that SNPs associated with markers of bone and joint health would be associated with levels of physical capability.
Conclusions Lower levels of physical capability at age 53 and inability to perform capability tests are associated with higher rates of mortality.
Further research is needed to identify the most effective interventions to improve levels of physical capability in mid-life and to test whether these interventions have a positive impact on survival rates.
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The scores of the ten questions are summed to obtain a total score that ranges from 0 to 100 (100 = high level of physical capability or "best" score).
Socioeconomic position (SEP) in childhood may influence the peak level of physical capability achieved in early adulthood, thereby affecting levels in later adulthood.
Childhood SEP, through its association with a range of factors, including growth and early life nutrition, may influence the peak level of physical capability attained in early adulthood, thereby affecting levels later in life [14].
Our use of a genetic variant of serum calcium provides additional insight into the effects of long-term raised serum calcium levels on measures of physical capability.
The aim of this review was to examine the associations of variation in levels of objective measures of physical capability at one point in time with subsequent health outcomes.
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