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To investigate the involvement of Sgs1 in the suppression of homeologous recombination, we assessed the levels of crossing over in three genetic intervals along chromosome III: HML ADE1-HIS4, HIS4-LEU2 and LEU2-MAT (Figure 3 and Tables S3 and S4) in various mutant strains.
Either case leads to a paradox: tandem duplications are generated through unequal (i.e., nonallelic) recombination, but levels of crossing over in these regions are exceedingly low.
The low levels of crossing over within and around knobs are also expected to limit the loss of knob repeats by unequal exchange (Charlesworth et al. 1994).
Note that QTL mapping on disomic chromosome XIII was not carried out on progeny of the original cross due to the very low levels of crossing over associated with generation of the disomy.
All four knobs map to regions that are gene-dense and normally experience high levels of crossing over (Fig. 2).
Similar(54)
This indicates that Delta and Beta toxins share a low level of crossed immunological reactions.
He and his partners sought out companies with lower levels of cross-shareholdings (which have been falling as banks unwind their holdings).
Lower levels of cross-linking can be the cause of this effect.
They share the same AA genome and show high levels of cross compatibility.
However, these inhibitors exhibit significant levels of cross-reactivity with related kinases, including Plk2 and Plk3.
Wear is controlled by levels of cross-shear motion and contact stress.
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