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For all six genes, the expression levels differentiated between follicular adenomas (macro- and micro-follicular) and follicular carcinomas (t-test, p<0.05).
Analysis of normalized gene expression data identified 219 probe sets (40 unannotated ESTs, 10 redundant probe sets, 169 annotated genes (Table S1) whose expression levels differentiated between the five groups.
CaM levels differentiated AD from control with a sensitivity of 0.89 and a specificity of 0.82 and were not dependent on disease severity or age.
Mollenhauer et al.[ 24] found that CSF mean alpha-synuclein levels and not total tau or Aβ42 levels differentiated Parkinson's disease and MSA from neurological controls (70% sensitivity, 53% specificity), whereas a combination of alpha-synuclein, tau protein, and age discriminated between synucleinopathies and neurological controls and Alzheimer's disease [area under the curve (AUC) 0.908].
The upregulated NGAL and KIM-1 protein concentrations increased over the time following ICU admission, whereby NGAL increased right from the time of admission (P < 0.0001); the KIM-1 levels differentiated between the non-AKI and AKI at the T = 24 hour time point for the first time (P = 0.008).
BBQ King Seemingly a world away in Sydney's Chinatown is BBQ King, its narrow front concealing a maze of interconnected dining areas on two levels, differentiated by the presence of tablecloths (upstairs) or lack thereof (downstairs).
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Most importantly, real-time RT-PCR analysis can yield accurate estimates of gene expression levels, differentiating between baseline levels of gene expression in normal tissue and increased levels in cancer cells [ 14, 15].
Using a thromboplastin-induced mouse model of pulmonary embolism, we show that urinary biomarker levels differentiate between healthy and thrombotic states and correlate closely with the aggregate burden of clots formed in the lungs.
This suggests that the commonly used gene-level analysis methods may fail to identify such relevant pathway-level differentiated genes.
In all cases except one (CASP10, F-test, p<0.05), the gene expression level differentiated not only between macro- and micro-follicular adenomas but also between follicular adenomas and oncocytic adenomas, as in the case of CDH16 and CRABP1 genes.
Education level differentiated cluster 1 ("high level of care") from cluster 2 ("absence of care").
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