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All patients, except one, had AST levels below the upper limit of normal.
Although more AEs of increased lipase were reported with insulin detemir, a minor increase in the median serum lipase levels (below the upper limit of normal) was observed across all groups, without apparent treatment differences (Supplementary Table 9).
In this short-term study, the proportion of patients achieving serum phosphate levels below the upper K/DOQI recommended value (1.78 mmol/L) in the placebo, 1 and 2 g iron magnesium hydroxycarbonate groups was 30.0, 52.4 and 81.0%, respectively.
All patients were required to have baseline serum creatinine levels below the upper limit of normal (ULN) and were excluded if alanine aminotransferase (ALT) levels were >250 U/l in the previous year.
The patients were divided into two groups based on the expression levels of the genes in question, as patients overexpressing the genes (expression levels in the upper tertile) and patients underexpressing the genes (expression levels below the upper tertile).
Ten patients (5·4%) presented with serum creatinine values greater than the upper limit of normal (ULN) and >33% above the value at the start of deferasirox treatment on two consecutive visits during the study: all had serum creatinine levels below the upper limit of normal (ULN) at the start of deferasirox treatment except for one who had received DFO during the core study.
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It is important to limit the values of buffer queue length/delay/jitter to a sustainable level below the upper bounds.
The administered mean dose had to be stepwise decreased in the first three days to maintain an aPTT level below the upper limit of 75 s; (Fig. 2a; left panel).
The buffer was not yet reduced to a level below the upper level of the chip.
In the caption to Figure 2B the statement means nothing to me: "The buffer was not yet reduced to a level below the upper level of the chip.
The procedure when and how the liquid was lowered was the same for each figure with micro chambers, except from the figures where it is indicated that "The buffer was not yet reduced to a level below the upper level of the chip".
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