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Sleep analysis was performed in 30-s epochs according to the American Academy of Sleep Medicine's (AASM) [19] standardized rules for scoring sleep stages and classification of waking and sleep into five levels (awake, non-REM stage [N1, N2, N3] and REM sleep).
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Thus, HS may replace mannitol due to its ability to increase osmolarity and decrease ICP while maintaining an appropriate serum sodium level for awake craniotomy.
The second patient on dose level 2 awoke with blind spots in his right visual field, on day 2 of selumetinib therapy.
An increase in arousal in response to hypercapnia [elevated arterial PCO2 (partial pressure of CO2) levels] during awake or sleep states is an important component of mechanisms designed to maintain acid base homeostasis.
The side of the brain that controlled the open eye had the activity levels of an awake bird, while the other side had brain waves characteristic of sleep, according to electroencephalogram recordings.
The heart rate increased after induction with TIVA, although the values did not reach the levels reported in awake unrestrained rabbits [ 37].
AVPU scale alertness level less than "awake".
In this study, we adjust baseline end-tidal pCO2 to 33 mmHg which is around 9 mmHg below the normal level in an awake monkey, because this gives optimal BOLD signal (Logothetis et al. 1999).
We performed six single factor, three level (one for each awake, low and moderate sedation levels) ANOVAs for translation in x,y,z directions and rotation in x,y,z directions.
The SSS is one of the most frequently employed scales to assess subjective alertness level and consists of a 7-point scale ranging from level 1 (feeling active, vital, alert or wide awake) to level 7 (no longer fighting sleep).
An AAI level above 60 indicates that a patient is fully awake; a level between 40 and 60 indicates light to moderate sedation, a level between 25 and 40 indicates deep sedation; and a level between 15 and 25 is satisfactory for surgery [ 10].
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