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The average score is dynamic and changes with the score level of the evaluated GPs.
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Real-time qPCR evaluation of the transcript levels of the evaluated genes revealed that their behavior could not be predicted solely by the demethylation status.
Except for miR-101 and miR-26b the expression levels of the evaluated miRNAs showed significantly weak to moderate inverse correlations with the expression levels of their putative target genes.
Accordingly, the transcript levels of the evaluated genes were reduced, although the reduction was found to be significant (P < 0.05, n = 3) only for TET1, TET3, and DMNT3b (Fig. S2).
The nonobserved adverse effect levels (NOAELs) of the evaluated carbamates were 12.5 mg/kg/day for both the female and male rats.
The same has happened with other parameters such as the educational level of the patients evaluated.
The level of sedation, evaluated based on the Ramsay sedation scale, did not show any difference between the two groups during the 24-hour infusion.
The level of BOS was evaluated on the basis of the Maslach Burnout Inventory (MBI score).
The level of disability was evaluated using the Swedish version of the Health Assessment Questionnaire (HAQ) [ 11].
In contrast, the levels of hydroxymethylation, evaluated the same way, show a rather different profile.
It provides an estimation of the average level of dominance of genes affecting the evaluated traits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com