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Generally SCRs maintain a basal level of sequence conservation (≥30% sequence identity), but there could be more conserved residues in proteins than the SCRs.
Peroxins show only a low level of sequence conservation.
An important biological role for the 5'-UTR of NR2A is further suggested by the unusually high level of sequence conservation between species.
High level of sequence conservation is a strong indication for homology.
This indicates a high level of sequence conservation, possibly due to protein functional or structural constraints.
Only six SNPs were identified in other genes of known function, indicating a much higher level of sequence conservation.
The high level of sequence conservation was surprising and suggests that these plasmids arose from a recent evolutionary event.
The Gα subunits in Ciona share a strong level of sequence conservation with those from other organisms including human, reflecting common structure-function relationships (Figure 2).
Further analysis shows that SMU.441, a MarR protein from the same operon as SMU.440, shares the same distribution pattern and very similar level of sequence conservation.
Finer genomic comparisons within the species showed a high level of sequence conservation; virtually all of the genome is common to the S. suis strains.
In this way, the constraint score reflects the level of sequence conservation within a particular region without penalizing unconstrained positions (Table 2).
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