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Aquavan gave patients a deeper level of sedation for a longer period of time than the comparison drug, midazolam, Guilford said.
All the patients maintained an acceptable level of sedation, measured by a BIS monitor.
The COMFORT behavior scale was used to titrate the level of sedation [20, 21].
To asses level of sedation in ventilated patients, we used the COMFORT behaviour scale.
Patients were excluded if it was felt that reducing the level of sedation was inappropriate.
Indeed, Payen et al. described a rising of BPS during procedure in patient under correct level of sedation [5].
Level of sedation is generally evaluated per 2 hrs (56%) and with use of a RASS scale (59%).
Neurological examination, including assessment of delirium, coma, brain stem reflexes and level of sedation were assessed daily for 14 days.
Fig. 3 Distribution of COMFORT-B scores per level of sedation and analgesia before and after the protocol implementation.
Practically, this level of sedation is preferred for ERCP sedation.
The level of sedation could be controlled easily.
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