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In contrast to the low level of recurrence in these melanoma samples at the individual gene level, we found that six pathways were shared by five of the samples, and four pathways (G protein, WNT, cadherin signaling and melanogenesis) were common to six (see Table 3).
Ovarian cancer is the most lethal gynaecological cancer due to late diagnosis and high level of recurrence (70% of patients).
pEMR is already established as resulting in a higher level of recurrence, but the risk appears even larger with malignancy.
Level of recurrence after surgery alone is comparatively high, so adjuvant radiation therapy is very important for the improvement of local control rates.
During asynchronous complex firing, there was also a high level of recurrence (Fig. 8C,D), indicating that activity at this mature stage was highly structured.
We found 595 (31.2%) recurrent mutations that can be collapsed onto 246 mtDNA positions, which is a 6.9-fold higher level of recurrence than expected by chance (p < 10−10).
Similar(49)
Using RT-PCR and sequencing, we detected this fusion in all 51 SFTs, indicating high levels of recurrence.
As a negative control, we tested whether the observed levels of recurrence exceeded what would be expected from a diverse collection of unrelated cells.
This analysis showed that synchronised firing had high levels of recurrence (Fig. 8A,B).
Worry about cancer recurrence, as assessed by the CARS, was also prevalent, with women reporting moderate levels of recurrence worry.
60 165 Initial follow-up at a later point such as 6 months also appears safe with similar levels of recurrence between 3 and 6 months.
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