Thus, glycolysis and the TCA cycle are uncoupled at the level of lactate, which is a primary circulating TCA substrate in most tissues and tumours.
Results show that the level of lactate in the construct centre varied with cell density, increasing as cell density increased.
Furthermore, cranberry juice decreased the plasma level of lactate, D-glucose, and two unidentified metabolites compared to apple juice consumption.
Sertoli cell functional proteins such as connexin 43, transferrin and androgen-binding protein expressions and the level of lactate were significantly decreased.
The levels of glucose as the main cell nutrient, and the level of lactate as the main cell metabolic product, were monitored continuously in the centre of the construct using a microdialysis probe.
We designed an experimental study first to investigate the serum level of lactate as a biomarker of MS progression and also to investigate the effect of methylprednisolone on serum lactate.
DOX treatment led to significant decreases in the ratio of heart weight to body weight and heart rate, and increases in blood pressure and the serum level of lactate dehydrogenase, a marker of cardiotoxicity, were recovered by yam extracts, especially in water extracts of D. alata.
The level of lactate dehydrogenase (LDH) released from astrocytes was measured to evaluate the cytotoxicity of ZnO NPs.
A significant rise in the level of lactate dehydrogenase (LDH) corroborated this finding (LDH: 76,100 IU/L N: 164 to 412 IU/L).
An interesting finding was the elevated interictal level of lactate (Lac) in the occipital visual cortex of a heterogeneous group of migraine patients (i.e., MwA, basilar-type migraine, migrainous infarction) [12], suggesting a deranged oxidative glycolysis.
But at that level of lactate, both at univariate analysis and after adjusting for other factors, still there was no significance of lactate >2.0 mmol/l to predict 72-h non-discharge (p = 0.06).
