Sentence examples for level of executioner from inspiring English sources

According to current concepts, apoptosis can be induced via at least two distinct, but interconnected pathways that activate different initiator caspases, that is, caspase-8 and -9, which converge at the level of executioner caspase-3, -6, and -7.

Of the eight patients who had suffered tumor reoccurrence within 7 months, three were also accurately predicted by APOPTO-CELL as being incapable of activating sufficient levels of executioner caspases.

Similar to siRNA-mediated knockdown of NFAT5 or S100A4, miR-568 significantly decreased the levels of metastasis executioners.

For instance, BCL2-like 14 (belongs) belongs to the pro-apoptotic branch of the Bcl2 family, cell death-inducing DFFA-like effector c (CIDEC), phosphatase and tensin homolog (PTEN), tumor protein p53 binding protein 2 (TP53BP2), all favor apoptosis at different levels, while caspase 6 (CASP6) is one of executioner enzymes for programmed cell death.

CsA completely blocked activation of executioner caspases in cancer cells as was manifested by decrease in protein levels of active-caspase-3 and 9 in EAC and MCF-7 cells, respectively.

Executioner(s):... Review with executioner(s) and alternates arrangements for their transportation and escort to the Execution Facility, and review with participants arrangements for security of executioner(s) and protection of their identities.

Initial drug discovery efforts were directed towards the identification of executioner caspase-3 inhibitors (Linton, 2005).

Activation of executioner caspases was 63.5% lower in cells treated with iRAGE before stimulation with CML-HSA.

So, they're leaving it up to the media organizations to play the role of executioner.

In addition, the activation of executioner caspase-3 was significantly increased at the same concentrations.

Apoptosome formation leads to the activation of executioner caspase-3, −6 and −7 [ 26].