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The level of encapsulation of the PCM RT21® was above 82 % for all of the samples prepared using the 10, 10.2, and 20 μm membranes.
The level of encapsulation ranged between 50 to 60%.
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The formulations that showed the highest levels of encapsulation were tested using in vitro release kinetics experiments with Franz diffusion cells.
As reported earlier, the release of a drug from polymeric micelles could be affected by the level of drug encapsulation, its physical state, the nature of the polymer and the level of polymer-drug compatibility [30, 53, 54].
This observation may explain the higher levels of drug encapsulation for the lower pH formulations.
The observed stalk cell and polar cell phenotypes suggest a defect at the level of cyst cell encapsulation.
The ability to interpret a visual encapsulation at low magnification is expected to depend on the level of expertise, just like knowledge encapsulations are not available yet to novices.
We found that transplanted fibroblasts increased the level of inflammation and glial cell encapsulation at the transplantation site, and reduced the diffusion of a 70 kDa dextran probe through the reactive tissue.
Increasing the level of softness of particle core gave higher encapsulation efficiency to the gold nanoparticles.
This enables the geometry control of encapsulation.
Fig. 1 Summary of encapsulation from macro- to nanoscale.
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