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From this study, it was concluded that an upfront regimen of TMZ and BV for unresectable glioblastoma was well tolerated and provided a significant level of disease stabilization.
Upfront administration of TMZ and BV in this challenging patient population provided a significant level of disease stabilization.
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Also, the whole blood RNase levels did not associate with any amount of disease stabilization.
Assessment of disease stabilization is more useful if disease progression is documented before the study entry.
Rates of disease stabilization need to be interpreted with caution in an indolent cancer; however, disease stabilization may be only a marker of antitumor activity.
A good rate of disease stabilization and an unacceptable toxicity was found in this setting [ 32].
After two months of disease stabilization, multiple brain metastases developed without any symptoms.
The results of this study highlight the importance of disease stabilization in CHB patients with hepatic decompensation.
In a retrospective analysis, a reduction of ≥80% was predictive of complete resolution of symptoms and disease stabilization [ 19].
Finally, mechanisms of a ceiling effect of sorafenib with disease stabilization remain unknown.
Our results showed a response rate of 25.4% and a disease stabilization of 38.2%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com