Typical peaks for manganese minerals were not detected, which suggest the manganese precipitates exist as amorphous materials or nanoscale materials with low levels of crystallization.
Lamellae are observed to melt from their edges, and this is proposed to be due to the inherent higher mobility at the crystal edges rather than differences in stability within the crystal due to different levels of post crystallization perfecting.
Considering 38% enhancement of the fracture stress with elevated temperature (from 60 °C to 100 °C), the temperature dependence of particular SAXS patterns further suggests that the elongation above Tg favors higher level of stretching-induced crystallization and better aligned microfibrillar structure, which competes with thermal-induced increased chain mobility.
However, increasing the concentration of clay beyond these levels retards the rate of crystallization.
DSC results indicate that the extent of crystallization increases with increasing neutralization level.
At the optimal component condition, the β-crystal content of PPR can reach the highest level of 92 % and the β-crystallization capability is improved by 56%.
By varying the crystallization temperature and level of supersaturation, three of the four polymorphs of carbamazepine (CBZ; 5H-dibenz [b,f]azepine-5-carboxamide) were crystallized from cumene (isopropyl benzene).
The crystallization lab conveyed concepts of crystallization fundamentals, i.e. crystallization rates, crystal growth and morphology.
Unfortunately, such type of crystallization provides precipitates with the properties (chemical composition, Ca/P ratio, crystallinity level, particle size distribution, etc).
We illustrate how crystal energy landscapes can help establish molecular-level understanding of the crystallization behavior of APIs and enhance the ability of solid-form screening to facilitate pharmaceutical development.
