Additional doses of α-chloralose (25 30 mg/kg, i.v). were administered to maintain an adequate level of anesthesia.
The level of anesthesia was additionally characterized by an absence of withdrawal reflexes to noxious pinch to the hindpaw.
No abnormal spontaneous activity was seen, and motor unit potentials had normal size, configuration and recruitment, with low firing frequency consistent with the level of anesthesia.
For recording sessions, the level of anesthesia was monitored with an ECoG electrode placed in the vicinity of the recoding area.
After a surgical level of anesthesia had been reached, the mouse was placed on a plastic plate with a heating pad covered with a cotton pad to maintain a body temperature of ~37.5 °C, recorded using a rectal probe.
Total intravenous anesthesia with propofol using target-controlled infusion technique guided by Bispectral Index monitoring ensures an optimum level of anesthesia.
Isoflurane is an alternative anesthetic that is less toxic than urethane, produces a stable level of anesthesia over extended periods, and is often used for recovery surgeries.
To determine the level of anesthesia attained in Xenopus laevis frogs with eugenol at different doses and by different routes of administration.
The question for the justices is what standard courts should use in evaluating the evidence from which to draw a conclusion on constitutionality, especially in light of evidence that pain can be avoided through a different combination of drugs and attention to a reliable level of anesthesia.
The ideal anesthetic agent allows rapid and pleasant induction (the process that brings about anesthesia), close control of the level of anesthesia and rapid reversibility, good muscle relaxation, and few toxic or adverse effects.
The day of the experiment, the two animals were anaesthetized (see above), and the EEG quality was verified; the level of anesthesia was adjusted to obtain a stable slow-wave state with clear "up" and "down" states (refer to Figs 1 and 2).
