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Hives and asthma tended to increase the risk of leukemia (relative risk [RR] = 2.1, 95% Confidence Interval [CI] 1.0 4.5 and RR = 1.6, 95% CI 0.8 3.5, respectively).
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An Ohio study examined the geographic distribution of childhood leukemias relative to population density, population growth, and rural/urban locale.
Calin et al.[ 13] carried out the first analysis of transcribed UCRs (T-UCRs) in cancer, demonstrating that approximately 9% of the 962 possible T-UCRs (sense + anti-sense) were aberrantly transcribed in either carcinomas or leukemias relative to normal tissue.
Niemann et al. [23] found that serglycin is distinctively expressed in acute myeloid leukemia (AML) relative to lymphoblastic leukemia.
Since increased process understanding favors process controllability, leukemia simplicity relative to solid tumors should favor its curability.
For leukemia, estimated relative risks exceed 50 per Sv shortly after exposure among those exposed in early life (UNSCEAR 2013; Wakeford 2013).
Because the CLL cells were not sorted, some changes in allele frequency during progression could be due to the leukemia expanding relative to the normal mononuclear cells.
When exposures were analyzed according to intensity-weighted exposures-days, applicators in the highest categories of exposure for fonofos (Mahajan et al. 2006a) and chlorpyrifos (Lee et al. 2004a) also had increased leukemia incidence relative to nonexposed applicators.
Applicators with the highest LDs of exposure for heptachlor/chlordane (Purdue et al. 2006), diazinon Beane Freeman et al. 2005, and EPTC (van Bemmel et al. 2008) had increased leukemia incidence relative to nonexposed applicators.
The temporal pattern is consistent with a multistage cancer model with benzene affecting a late stage in the induction of leukemia; the relative rate of leukemia per unit exposure increases with age at exposure and decreases with time since exposure (Thomas 1988).
After earning a PhD studying feline leukemia virus in relative obscurity at the University of Washington, Seattle, I found myself as an American ex-pat in London, examining the ins and outs of cellular suicide in the lab of a famous man in a prestigious institute.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com