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Eligible residents were prospectively enrolled with informed consent and letters of information, in accordance with Western University's REB regulations.
Important among these are the Cartas de Relación ("Letters of Information"), sent by Hernán Cortés to the Holy Roman emperor Charles V, and the Historia verdadera de la conquista de la Nueva España (1632; The True History of the Conquest of New Spain) by Bernal Díaz del Castillo.
Nationally, letters of information and invitation were sent out from the Office of Academic Affiliations to all physician trainees for whom addresses were available.
Letters of information and questionnaires were sent to 3,889 persons by post, and a reminder was sent two weeks later, which resulted in a total response of 2,387 (64%) participants.
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Additional protocols and modifications to the letter of information and informed consent related to the reported study were accepted by the same committee on May 17 , 2005and January 16 , 2006
Questionnaires in paper format were put in an envelope together with a letter of information and an informed consent form, and placed in each employee's personal shelf at work.
They received a letter of information and were asked to give informed consent to leave blood and have it stored in a so-called Biobank.
Participants were sent a Letter of Information detailing the goals of the study and informed consent was obtained verbally from participants.
During the first visit, a letter of information addressed to the children and their parents, the informed consent and the nutritional questionnaire were handed over to the teachers.
A letter of information targets the patient and his family, another one targets the general practitioner.
A letter of information outlining the study protocol and potential risks was provided to these eligible patients.
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