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Only interactions tagged with "Synthetic Lethality" were used, resulting in a total of 15,196 interactions.
Both clonogenic-cell survival and growth delay were measured as indicators of tumour response and depression in WBC count and acute lethality were used to indicate normal-tissue response.
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In this assay, Artemia nauplii are exposed to test compound and lethality is used to estimate cytotoxicity.
Complementation/noncomplementation of mutant lethality was used to narrow the loci to as fine a scale as possible.
To evaluate the MnP-I-PVAA and F-MnP effect on cytotoxicity reduction, erythrocytes lysis and brine shrimp lethality tests were used [2].
To evaluate free and Ca-alginate immobilized MnPs effect on cytotoxicity reduction, erythrocytes lysis and brine shrimp lethality tests were used [ 5].
To determine if the absence of Fus1 altered latency of death after WBI, higher doses of 9 and 10 Gy that cause high rates of lethality in WT mice were used.
In the screen for PAX7-FOXO1 genetic modifiers, the UAS-PAX7-FOXO1 and Myosin Heavy Chain-Gal4 transgenes were used, and lethality assessed, as previously described (Avirneni-Vadlamudi et al. 2012).
The Actin-Gal4 constitutive driver, the Elav-Gal4 and Da-Gal4 pan-neural drivers [26], [27] and the BG380-Gal4 motoneuron driver [28] were used to assess lethality.
In the analysis, scale scores of aggression, irritability and lethality of suicide attempt (item 7b) were used.
I-Ab tetramers presenting an immunodominant peptide (aa 641 655) from West Nile Virus (WNV) envelope protein (E641 I-Ab) wE641 I-Abbecause werelethality increases over the lifespan of mice and huseds, making it a useful model for investigating age-related defects in susceptibecauseto viral infection and vaccine efficacy (Brien et al., 2008, 2009; Uhrlaub et al., 2011; Suthar et al., 2013).
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