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Hence, with the rationale of determining easy and economical protection against ENPs exposure, the amelioration effect of the antioxidants (curcumin and vitamin-C) against the nano-TiO2 and nano-ZnO induced ROS and lethality were investigated in Caenorhabditis elegans.
As a single intraperitoneal injection of LPS with D-galactosamine has been perceived to be capable of inducing endotoxin shock in mice, the impacts of constitutive expression of IL-32α and subsequently produced TNFα on endotoxin lethality were investigated.
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The genetic interactions between 38 query genes that are members of the histone acetylation/deacetylation complex were investigated using diploid-based synthetic lethality analysis on microarrays.
In the present study, the root extracts were investigated for the phytochemicals that may be present the antibacterial, anticandida activity using 96 wells microtitre plate method and cytotoxicity using brine shrimp (Artemia salina) lethality assay.
To assess the effect of TGR on lethality in mice, 3-h and 8-h cultures of IDM mutants, incubated in the same liquid media as that used in the in vivo study, were investigated.
FecE mechanism of action regarding the inhibition of Bax-induced yeast lethality remains to be investigated but may be related to its ATPase activity, considering the various implications of ATPases in intracellular signaling pathways.
The extent of light-induced damage was investigated by cell lethality, by cell membrane permeability, and by protein inactivation.
Whether a high level of serum IgG on admission is an independent risk factor for an increased lethality in critically ill patients, as shown in our analysis, needs to be investigated in further studies.
Additional approaches for targeting the hypoxic tumour microenvironment are being investigated in pre-clinical and clinical studies that have potential for producing synthetic lethality in combination with anti-angiogenic therapy as a future therapeutic strategy.
In this study, the lethality as well as biochemical and histopathological effect of Egyptian cobra (Naja haje; N. haje) crude venom at a sublethal dose have been investigated on liver and kidney of male mice.
The functional role of JNK activation in PEITC lethality was then investigated using both pharmacological and genetic approaches.
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