Suggestions(1)
Exact(2)
Furthermore, embryonic lethality was a main drawback of the conventional GEM models.
Thus, we concluded that the embryonic lethality was a rare event that was difficult to relate to the observation of frequent early death in mito-mice∆.
Similar(58)
Synthetic lethality is a lethal phenotype caused by the combined effects of mutations in two or more genes.
Synthetic lethality is a term to describe the combined lethal effect of two genetic variations that are otherwise non-lethal when occurring in isolation.
Synthetic lethality is a genetic interaction wherein two otherwise nonessential genes cause cellular inviability when knocked out simultaneously.
Here an attempt has been made to study the characteristic features such as physical dimensions, mechanism of action of this weapon and to compare its penetrating ability with that of air gun, whose potential lethality is a well-documented fact, using the ballistic gelatine blocks at various ranges.
"Severity of infection, including lethality, is a complex biologic phenomenon involving pre-existing immunity to pathogens, individual susceptibility, pathogen dose, etc.," said Kawaoka in an e-mail reply to Science.
Synthetic interactions (such as synthetic lethality) are a hallmark behavior of genes involved in a common function [40].
In this model system, lethality is a rather clear-cut parameter and, based on the number of mice killed, strains are classified as non-killer (<2 of 10 mice killed), killer (>8 mice killed) [49] or intermediate.
Our finding that ctf7 ctf18 double mutant cell lethality can be bypassed by additional deletion of RAD61 indicates that ctf7 ctf18 lethality is a result of cohesion defects and not severe DNA replication defects since rad61 deletion specifically reduces ctf7 mutant cohesion defects [36].
Lethality is a crucial factor to characterize the biological essentiality of a protein.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com