Sentence examples for lethality provides a from inspiring English sources

The global lethality provides a perspective of a particular cancer with respect to the other cancers, whereas, the local lethality is specific to each cancer type.

In summary, while synthetic lethality provides a logical explanation for the lack of certain co-occurring (i.e. mutually exclusive) combinations, in general synthetic lethality is a broader concept.

In summary, synthetic lethality provides a conceptual framework for discovering drugs that selectively kill cancer cells while sparing normal tissues and for tackling 'undruggable' targets.

Synthetic lethality provides a conceptual framework for using this information to arrive at drugs that will preferentially kill cancer cells relative to normal cells.

In the case of antibiotics, synthetic lethality provides a basis for why this would be the case, and analogous effects may be at work in the case of anticancer drugs believed to act on multiple signaling proteins, such as imatinib and sunitinib.

Synthetic lethality provides an opportunity for therapeutic intervention of MYC-driven cancers.

The Xist-induced lethality then provides an efficient selection strategy for recovering mutations abrogating the silencing pathway of Xist and, therefore, preventing Xist-dependent cell death.

For example, synthetic lethality theoretically provides an avenue for targeting cancer-causing loss-of-function mutations, such as mutations leading to the inactivation or loss of a particular tumor suppressor protein.

In their seminal paper, Lee Hartwell and Stephen Friend proposed that synthetic lethality may provide a solution [30].

This developmental lethality assay thus provides an efficient 'medium-throughput' screen for testing subsets of drugs that are selected from high-throughput screens (such as the MC65 cell assay) and might be neuroprotective against amyloid toxicity in vivo.

RNAi screen provides a more direct way of establishing synthetic lethality relationships.