Sentence examples for lethality it is from inspiring English sources
Given their high lethality, it is not surprising that rates of hanging and firearms were higher for suicide than for suicide attempts.
Even if one assumes that Trp53-mediated apoptosis is significantly relevant for the mechanism of Trp53 rescue of Brca1 lethality, it is unclear how this Trp53 mechanism relates to tumorigenesis due to Trp53 loss.
Since RFP-PeriCT RNA did not cause necrosis or lethality, it is plausible that the observed developmental delay was caused, at least partly, by reduced proliferation of RFP-PeriCT-expressing cells.
While we cannot rule out a more subtle skeletal muscle phenotype due to the early lethality, it is possible that the skeletal muscle specific miR-1 family member, miR-206, can compensate for the loss of miR-1 in this tissue.
Because the constitutive knockout of Hsp90b1 is responsible for peri-implantation embryonic lethality, it was not yet known whether Hsp90b1 is a functionally important maternal factor.
For studies of early developmental phenotypes or lethalities, it is essential to be able to identify the chromosome involved in the aneupoloidy or uniparental inheritance at any selected time during development.
The major hemorrhagic protease, termed hannahtoxin, is a 66-kDa zinc-dependent metalloprotease that exhibited species-specific lethality, where it is highly lethal to rabbit but not to mice at comparable doses [ 56, 57].
The data described above show that second generation CKO embryos have developmental defects and high rates of early embryonic lethality, however, it is still possible that defects in the CKO females also contribute to the early lethality observed in these mice.
Loss of Dbx1 leads to perinatal lethality due, it is assumed, to loss of preBötC and other hindbrain glutamatergic neurons.
The deletion of EGFR is also associated with embryonic or early postnatal lethality, although it is probably not related to cardiac effects [ 4].
Moreover, PrV can infect a broad range of vertebrates resulting in a uniform lethality but it is generally considered as a non-pathogenic agent for man [ 3].
