These experiments described in these studies were previously performed in Balb/C mice although the results varied depending on the strain of virus used and lethality was often very low or absent in most cases.
Therefore, lethality of lung cancer is often attributed to late diagnosis, metastasis, and the occurrence of drug resistance [ 8].
One possibility is that in highly conserved proteins the occurrence of double mutations, as observed in recessive disease genes, is often associated with lethality, in which case a disease condition will not be observed.
Interestingly, HSP downregulation is often associated with toxicity and lethality and can result in disease itself.
Although not directly related to the lethality-essentiality rule, the scale-free model of biological networks is often used to explain the robustness of these networks.
Constitutive expression systems have proven useful, but it is often observed that the expression of oncogenes may cause serious tumors and early lethality, preventing the complete characterization of their effects.
Emb commonly leads to embryonic lethality, while Stu mutants are often associated with defects in the development of gonads (sterility) or neurons in the ventral nerve cord (uncoordination) [25], [26], [27].
The group's lethality is undeniable.
A weapon's lethality is, ultimately, not up to the object itself.
Moreover, synthetic lethality is also observed with Kar3Δ deletion.
