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Together these observations indicate that the suppression of lethality is dependent on partial ROL-3 function, and also implies that rol-3 s1040) rol-3 s1040tured animalsare essentially null for ROL-3 funcultured
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We first examined whether lethality was dependent on plasmid selection following expression of BRCA1 (Fig. 3A).
A series of test injections showed that the embryonic lethality is concentration dependent, ranging from 30% at 1 ng/µl to 100% at 20 ng/µl (see Supporting Information, Table S1).
As engineered TC-repressible lethality in these strains is dependent on the expression of tTAV, these minigenes limit this phenotype to females.
D-galactosamine (GalN /lipopolysaccharide (LPS -induced LPS -inducedd acute lethalitylure is dependent on endogenously produced inflandacute cytokines.
Involucrin-Cldn6 (Inv-Cldn6) transgenic mice also suffer skin barrier dysfunction, the severity/lethality of which is dependent upon the level of Cldn6 overexpression [15], [16].
Deficiency in either protein results in embryonic lethality, but this lethality is totally dependant on p53.
A company called Armalite built a machine that was "lightweight, air-cooled, gas-operated, and magazine-fed" that was so good "its lethality was not dependent on good aim or ideal combat conditions".
This lethality was strain dependent, as miR-1-1 null animals on a mixed background (129/BL6) survived at normal Mendelian ratios until weaning.
For example, Nup96-dependent lethality is specific to D. simulans and D. sechellia (Barbash 2007).
This screen is based on the underlying assumption that the OK107 > unf-induced lethality is due to the unf-dependent activation of target genes and other indirectly regulated downstream genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com