Sentence examples for lethality from the from inspiring English sources

However, the identification of HAM1/ham1; hand/ham1/ham1ham1/ham1; HAM2/ham2 individuals, and the data collected from outcrossing eliminated the possibility of a complete male gametophytic lethal phenotype, although there was some implication of high gametophytic lethality from the sesquimutant plants.

This result suggests that the lethality from the deletion of Cdk2ap1 is not due to the abrogation in the hatching process.

The concept of inferring synthetic lethality from the mutual exclusivity is novel even though several studies (Ciriello G et al., Genome Research 2012; Unni AM et al., eLife 2015) asserted those two are related.

The objective of the present study was to further scrutinize this concept in an experimental protocol in which we hypothesized that a selective ablation of the tissue repair response should lead to lethality from the nonlethal, moderately toxic doses of 150 and 300 mg/kg TA.

Mice null for Foxc1 or Foxc2 and heterozygous null/wildtype for the other gene experience lethality from E12.0 to E12.5; the Foxc2 null mice particularly had a shortened OFT and smaller right ventricle (Seo and Kume, 2006).

This result suggested that embryonic lethality resulted from the lack of functional Noc4l alleles.

Further support for the association of P-CTD cleavage and lethality comes from the rescue of both phenotypes in the def1Δ strain, previously shown to be defective for ubiquitin-mediated RNAPII degradation following DNA damage [13].

Control matings showed that some of the early lethality originated from the subpopulation of embryos with homozygous Tek-Cre transgene, a problem that has not previously been reported for this commercial mouse strain.

Since expression of Cre recombinase does not result in lethality in other conditional mouse strains, and since the Jackson Laboratory currently has another Tek-Cre mouse strain in development, which is stated to be viable as Tek homozygotes, we suggest that this lethality originates from the site of insertion of the Tek-Cre transgene, which may disrupt the function of an essential gene.

We retrieved the human orthologs of the mouse lethality genes from the Mouse Genome Informatics database [ 29].

We conducted a hypergeometric test on the human orthologs of the mouse lethality genes from the Mouse Genome Informatics resource [ 29].