Sentence examples for lethality data are from inspiring English sources

A far larger contribution of synthetic lethals in providing model refinement strategies is thus expected as more synthetic lethality data are becoming available.

By analyzing the mutation patterns with different levels of recessive lethality, earlier published conclusions based on partial data are found to remain valid.

The accumulated lethality was calculated and the obtained data were well described by the first order kinetic model.

However no data is available on how and what stage lethality occurred.

The data is consistent with our hypothesis that PRKDC loss-of-function synthetic lethality is reliant on high MYC expression levels.

The data were analyzed using a generalized linear model with a quasi-binomial error structure to test the effect of strain on embryonic lethality.

Synthetic lethality data for this study was obtained from the BioGRID database (version 2.0.46) [ 17].

While the lethality data suggested that genes that are more important determinants of fitness have greater environmental robustness, our analysis of Ka/Ks showed the opposite pattern.

RNAi-mediated knockdown of Unc-104 in neurons (elav-Gal4, D42-Gal4) but not in muscles (Mhc-Gal4, 24B-Gal4) isufficientntoto induce lethality (data not shown).

This demonstrates that our approach has broader utility and can be applied to other synthetic lethality data sets.

The AN2R construct was also unable to rescue Roc1aG1 lethality (data not shown), consistent with the failure of the AN2R protein to bind Cullin.