Sentence examples for lethality compared with from inspiring English sources

There was no evidence for differences in the number of available knockout models for the 53 orthologs that were associated with lethality compared with the 97 non-lethal genes (median 2 [interquartile range 1 to 3] versus 1 [interquartile range 1 to 2], Mann-Whitney U test p-value = 0.13), so it is not likely that the first group had been studied far more extensively than the latter.

These transgenic LLs can now be used to evaluate the fitness costs of transgenic lethality compared with radiation-based sterility.

Three of these, ΔFTT0482c, ΔFTT1538c, and ΔFTT1597, showed a statistically significant reduction in lethality compared with the wild-type strain and can, thus, be considered novel virulence factors.

This latter point is relevant because BACE1-/- BACE2-/- douBACE1-/- BACE2-/- have enhanced postnatal lethality compared with BACE1-/- BACE2-/-nockout mice [ 39].

In experimentally infected mice, the variant showed delayed onset of symptoms, a reduced viral load and attenuated lethality compared with the wild-type.

In keeping with the cooperative functions of Mus81 and Sgs1 in yeast, him-6/ rtel-1 double mutant worms also show an elevated level of meiotic RAD-51 foci and increased embryonic lethality compared with either single mutant (Barber et al. 2008).

This current study corroborates that radiation combined with wound trauma potentiates lethality compared to radiation alone [ 5].

Comparable doses of LT and ET together had previously additive effects on lethality compared to LT alone [18].

Among these analogs, the compound AA9 showed the best toxic activity on L. major (LD50 = 3.34 μM), which represents a 9 fold higher lethality as compared with its parental AA1 (Fer-1) compound (LD50 = 28.75 μM).

During our studies, we found that prolonged loss of Cdk5 was associated with handling induced seizures and lethality when compared with controls.

In line with this, a Brca1 truncation mutant lacking the second BRCT repeat shows a delayed embryonic lethality when compared with Brca1-null mutants (Hohenstein et al, 2001).