Sentence examples for lethality can be from inspiring English sources

There is experimental evidence showing that expression of H. pylori OMPs in E. coli is lethal, and that this lethality can be suppressed by removing the C-terminal strand.

Double deletion of RAS1 and RAS2 is lethal, and just like the deletion of AC, this lethality can be rescued by mutations in the Bcy1 regulatory subunit of PKA, which make PKA activity independent of cAMP (reviewed by Broach & Deschenes, 1990).

But more specific hypotheses for the observed synthetic lethality can be envisioned.

Using a tamoxifen-inducible Cre line we show that embryonic lethality can be rescued early in gestation but not late.

However, in the presence of Cre recombinase, the embryonic lethality can be rescued by neo excision, while still maintaining Smn exon 7 alternative splicing via our introduced mutations.

Thus no conclusion about the most prevalent phenotype of the 45,XO karyotype, namely the early lethality, can be reached by studying these patients.

We assume that the gene pairs exhibiting synthetic lethality with arp1 and jnm1 (synthetic lethality interactions) can be divided into two groups, one of them representing genes involved in spindle migration and the other representing genes with no direct involvement.

In addition, as many basic cellular processes are ultimately required for viability, synthetic lethality screens can be used to study a wide range of processes.

Similar to lgl and brat tumors, those arising from l(3)mbt mutations result in larval lethality and can be allografted (Fig. 1B).

However in some cases, such as whole-gene deletion assays that may induce lethality, selection can be useful for both identifying and maintaining HR events.

Our results also suggest that the synthetic dosage lethality screen can be used to isolate physiological targets of a specific proteolytic pathway.