Sentence examples for lethality because the from inspiring English sources

Hematotoxicity could be the direct toxicity of these compounds followed by sinusoidal congestion and hepatoxicity such as, necrosis, inflammation, toxicities to other organs and even lethality because the delivery of oxygen to tissues is impaired.

This difference was not due to cell lethality because the viability (measured by the number of colonies formed after plating) was the same after 8 hours of induction (data not shown).

It is also clear, however, that the environment plays an important role in the lethality, because the Kaiser lab never observed any triple knockout mice that survived past weaning.

According to Smyth et al. [ 29], null mutation of LAMC1 causes embryonic lethality because of the absence of the basement membrane and failure to differentiate the endoderm.

However, intense expression of the Mu A and Mu B genes, even when located in trans, leads to host cell lethality because of the overly efficient replicative transposition of the mini-Mu LER) units (Akhverdyan et al. 2007; Lee 2002).

Loss-of-function mutations of MEF2C in mice result in embryonic lethality because of the cardiac malformation, and skeletal muscle-specific deletion of MEF2C will cause improper sarcomere organisation and weakened M lines.

It is also possible that lethality results because the Mcm4 and Mcm5 proteins lie opposite each other in the hexameric ring (Bell and Botchan 2013).

First, we used an epidermal-specific RNA interference (RNAi) strain [7] to knock down wsp-1 and unc-34 function, but we observed no lethality, perhaps because the promoter used in this strain is active too late in development to confer robust RNAi sensitivity.

The severe aneurysms within the aortic arches are very likely the cause of the embryonic lethality, because oxygen and nutrient supply must be severely compromised in the conditional Ilk mutants.

These survivors do not appear to have acquired linked genetic suppressors of lethality because they continue to transmit the R11 insertion to homozygous progeny at reduced frequency.

A dosage compensation defect does not appear to be the direct cause of hybrid lethality because X chromosome transcripts are not preferentially affected in lethal hybrids (Wei et al. 2014).