These genes control lethality at two different stages of apple seedling development, sl1 after and sl2 before germination, and they both interacted with another locus, sl3, whose map position was not identified.
However, effectors containing the p basal promoter could not promote complete lethality, whereas systems with effectors containing hs43, which gave no functional transgenes in D. melanogaster [ 6], caused complete lethality in medfly at different stages of development.
Although inactivation of each individual VEGFR can cause embryonic lethality at mid-gestation, they have different functions [47], [48].
However, at different levels of par-1 knockdown, genes independent of RNAi may influence lethality.
We found that lethality of gln1 -2 was partially rescued in sse1 Δ cells, whereas no effect was observed for pro3 -1 and ugp1 -3 at different nonpermissive temperatures (35, 36, or 37°; data not shown).
As summarized in Table 5, mibefradil (T-type) showed the highest lethal activity (36.8±5.7% lethality at 1 mM) followed by verapamil (L-type, 24.3±5.1% lethality).
Roundup at different concentrations (0, 1, 2, 3, 4 and 8 mg acid equivalent (ae)/L), tested in a 2 × 6 factorial design in the presence and absence of predator stress, induced concentration-dependent lethality in tadpoles.
However, it is interesting that different types of death statistics (global lethality vs. local lethality) show different results.
