Sentence examples for lethality and developmental from inspiring English sources

Certain of these lineage-specific genes may have direct roles in the lethality and developmental delay observed in Drosophila following bacteria ingestion.

Our data strongly suggest that HlyA is a virulence factor in C. elegans infection leading to lethality and developmental delay presumably through intestinal cytopathic changes.

The GacA regulon of Pf-5 includes many other secondary metabolites, toxins, secretory systems, and exoenzymes that could contribute to the gacA-regulated lethality and developmental delay observed herein.

Here, we show that the lethality and developmental delay caused by ethanol exposure are largely due to oxidative stress.

This is not particularly surprising, because our previous work demonstrated that the critical developmental periods for ethanol-induced lethality and developmental delay were separable (McClure et al. 2011).

Bar-Ilan et al. [ 9] demonstrated that various sized gold and silver particles were able to affect zebrafish development, causing lethality and developmental anomalies in body axis shape and heart functionality.

However, the early embryonic lethality and severe developmental defects associated with cilia disruption has hindered progress in exploring cilia functions in late development or in adult tissues.

Indeed, considering that p57KIP2 null mice have increased embryonic lethality and gross developmental defects as compared with p21CIP1/CDKN1A and p27KIP2/CDKN1B null mice, it appears that the cellular roles of p57KIP2 surpass that of the other Cdk inhibitors.

By morpholino-mediated knockdown, we demonstrated that naa10 morphants displayed increased lethality, growth retardation and developmental abnormalities like bent axis, abnormal eyes and bent tails.

In this study we use experimental mouse chimeras made from wildtype and Pax6-null embryos to circumvent early lethality and assess the developmental potential of mutant cells in the construction of the cerebellum.

Inactivation of the orthologous genes in Drosophila and C. elegans were surprisingly not associated with embryonic lethality and no major developmental defects have been reported for the loss-of-function mutants [ 59, 96].