The world is a lethal testing ground and the nuclear family is just another weapon.
Ultimately, the BoNT ALISSA might help to reduce animal use for the associated lethal test procedure.
Even after a potentially lethal test, such as resistance to FOM, I was able to collect seeds from 144 of 236 tested C-T BC1 hybrids.
Thus, neither VC nor VDC is mutagenic in the mouse at the stated exposure levels as measured by the dominant lethal test.
The mutagenic activity of vinyl chloride (VC) and vinylidene dichloride (VDC) at three exposure levels was assessed in fertile male CD-1 mice with the dominant lethal test.
The Drosophila sex-linked recessive lethal test also gave negative results in studies that involved three routes of administration: inhalation, feeding, and injection.
Of the different assay systems available, the classical sex-linked recessive lethal test deserves priority, in view of its superior capacity to detect mutagens.
LC50s values from the embryonic lethal test dramatically decreased from 1.46 mg/L (CI: 0.81 2.10) to 0.43 mg/L (CI: 0.37 0.49) at 8 d after AgNP exposure when embryos started to hatch.
The numerical sex-chromosome anomaly (NSA) method is useful not only in the study of ND but also in detecting breakage-derived chromosome losses induced in females, where the dominant lethal test is not easily applicable.
Lethal challenge tests entail the use of specialized containment facilities for the safe and secure handling of the challenge strain.
