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The value refers exclusively to dead eggs and lethal malformations (pursuant to the definition in DIN ENISO 15088) after 96 hpf in water in per cent [4, 9].
Stillbirths due to intrauterine fetal death (IUFD) were also excluded (n = 72), as were infants with lethal malformations (n = 3; anencephaly, Potter syndrome and trisomy 18).
In the IPD MA the Swedish RCT was represented by mortality corrected for lethal malformations but the Dutch RCT was represented by uncorrected mortality figures.
The mortality rate was 0.31% when corrected for lethal malformations and 0.09% after the additional correction for death before admission to the maternity clinic [ 12].
We excluded 102 infants due to a non-reactive CTG at admission (n=60), missing case records or CTG tracings (n=31), precipitate deliveries (n=7) or lethal malformations (n=4).
We excluded 102 infants because of a non-reactive cardiotocogram (CTG) on admission (n = 60), missing case records or CTG tracings (n = 31), precipitate deliveries (n = 7), or lethal malformations (n = 4).
Similar(51)
Agnathia-otocephaly, a rare, sporadic and lethal malformation, is characterized by microstomia (small mouth), aglossia (absence of the tongue), agnathia (absence of the lower jaw) and abnormally positioned ears.
Bilateral renal agenesis/hypoplasia/dysplasia (BRAHD) is a relatively common, lethal malformation in humans.
Fetus exposed to irradiation has a greater risk of lethal malformation in utero and malignancy in the future [ 13].
Of the 78 babies born after 23 completed weeks for whom stabilisation was withheld, six (8%) had a potentially lethal malformation known before, or apparent at, birth.
Mutations in the U4atac snRNA component of the minor spliceosome were recently shown to cause a lethal malformation syndrome called microcephalic osteodysplastic primordial dwarfism type 1 (MorD1) or Taybi-Linder syndrome (TALS) (Edery et al, 2011; He et al, 2011).
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