Sentence examples for lethal infusion from inspiring English sources

At 4 h of mechanical ventilation, soon after the animals had received a lethal infusion of saturated potassium chloride, the final BAL was performed with 20 ml/kg of cold phosphate-buffered saline.

The increase in the plasma concentration of fibrinogen during treatment with rhAPC is consistent with the findings of Taylor and colleagues, who concluded that APC prevents both the coagulopathy and the lethal effects of infusion of live E. coli in baboons [ 19].

At time 0 (T0), all animals were started on a continuous 24-h infusion of lethal toxin (LT) and edema toxin (ET) together.

Fig. 2 Comparison of the survival times in animals treated with anthrax immune globulin (AIG, closed circle) or intravenous immune globulin (control, open circle) administered 4 h before (a) or 2 h (b) or 5 h (c) after the start of a 24-h infusion of lethal and edema toxins together.

Lethal and edema toxin infusions were prepared and administered as described previously [4].

We therefore tested AIG in sedated, mechanically ventilated canines challenged with 24-h B. anthracis lethal and edema toxin infusions and supported for 96 h with a previously demonstrated protective regimen of titrated normal saline and norepinephrine.

More survivable cases, occurring with lower infusion rates, have replaced lethal PRIS with multiple clinical manifestations.

At a dose of 8 mg/kg, a bolus infusion of carfilzomib was lethal to 44% of rats, whereas the same dose given over 30 min was not toxic.

In a baboon model of potentially lethal septic shock induced by intravenous infusion of Escherichia coli, administration of recombinant TFPI 6 mg/kg significantly attenuated the coagulation response, decreased damage to target organs, including the lung, and reduced mortality [ 8].

Early studies in dogs demonstrated that infusion of thrombin blocks the lethal inflammatory response to endotoxin [ 30].

In contrast, organ damage was prevented in animals given a lethal dose of E. coli plus an infusion of Activated Protein C (Fig. 5b).