Sentence examples for lethal inflammatory from inspiring English sources

Early studies in dogs demonstrated that infusion of thrombin blocks the lethal inflammatory response to endotoxin [ 30].

Accordingly, BALB/c-TGFβ1 KO mice develop lethal inflammatory hepatitis that was not observed in other genetic backgrounds.

We previously showed that SPRET/Ei (S) mice, unlike C57BL/6 (B) mice, are extremely resistant to lethal inflammatory shock induced by TNF (Staelens et al, 2002).

We here present genetic data showing that concomitant ablation of MMP9 (gelatinase B) and the serine protease plasmin results in lethal inflammatory mass lesions in the colon.

In addition, because MMP9 clearly rescues Plg −/− mice from developing lethal inflammatory mass lesions in the colon, we investigated the expression pattern of MMP9 in inflamed colon lesions of Plg −/− mice.

In addition, TGFβ plays a principle role in immune cell homeostasis and function with, mice developing a lethal inflammatory disorder when TGFβ1 or its receptors are knocked out [ 73, 74].

TGF-β1 is considered a major anti-inflammatory cytokine, as TGF-β1 knockout mice suffer from a lethal multifocal inflammatory disease (Kulkarni et al, 1993; Letterio & Roberts, 1998) and the blockage of TGF-β1 signalling in T cells or in bone marrow results in similar multifocal inflammatory responses (Gorelik & Flavell, 2000; Shull et al, 1992).

Virulent PRV infection induces a specific and lethal systemic inflammatory response in mice.

Taken together, these experimental data suggest that fetuin-A is protective against lethal systemic inflammatory diseases.

Recently, HMGB1 has been established as a late mediator of lethal systemic inflammatory disease.

In a recent study, Duprez et al. revealed that the RIPK-dependent increased necroptosis perturbed lethal systemic inflammatory response syndrome.