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Insertion of foreign DNA fragments within the ORF of the gene disrupts the lethal effect of the expressed protein.
The US and UK had tried to prevent Syrian officials buying two precursors needed to dispense sarin, however substitutes could retain the lethal effect of the gas.
It was found in this study that the lethal effect of the oral cancer cell lines OEC-M1 induced by AZ-1 was mediated through the cell cycle arrest and apoptosis pathway.
Functional cellular studies with outer membrane-, cytoplasmembranerane vitality- and redox-specific fluorescence dyes revealed that the lethal effect of the isolated antimicrobial peptides is due to membrane permeabilization and inhibition of redox-driven bacterial respiration.
Nude carps, a genotype of common carp which are devoid of scales, have been banned from farmed populations of carp in Europe due to both the lethal effect of the N (nude) gene when in homozygous state, and to the negative pleiotropic effects on growth and survival (especially in harsh conditions) of this same gene in the heterozygous state, which produces the nude phenotype.
Lethal effect of the entomopathogenic nematode, Steinernema feltiae, against prepupae of Helicoverpa armigera (Hb) (Lepidoptera: Noctuidae) in soil was evaluated.
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The lethal effects of the drug on the two cell lines were comparable.
In 2008/2009, Schmidt and colleagues published a study reporting lethal effects of the microbial Bt toxins Cry1Ab and Cry3Bb on the coccinellid biological control organisms Adalia bipunctata.
In 2008/2009, Schmidt and colleagues [1] published a study reporting lethal effects of the microbial Bt toxins Cry1Ab and Cry3Bb on the biological control organisms Adalia bipunctata, a lady beetle.
The lethal effects of the SMC challenge were further characterized for axenic UH18301 in unamended seawater.
Thus, the bacterial SOS response to β-lactam antibiotics results in filamentation that allows the bacteria to reduce the lethal effects of the drugs [15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com