Sentence examples for lethal changes from inspiring English sources
Since no viral functions are required for propagation of recombinants in bacteria, viral mutants with lethal changes in cis- or trans-acting elements can be isolated, as well as partially or conditionally defective mutants.
This correlates to the proportion of unobserved lethal changes at a given gene (Eilertson et al. 2012).
Structural changes were reported by study investigators as malformations (defined as rare and/or probably lethal changes), anomalies (defined as relatively frequent minor differences from "normal") and variants (defined as alternative structures occurring regularly in the control population).
Increased expression at lower concentrations of lead is beneficial as part of an adaptive, mitohormetic response, whereas at higher concentrations, higher expression levels of PGC1α, when sustained for a prolonged period of time, characteristic of chronic exposure, lead to lethal changes in cellular metabolism.
Thus, important positions for H-bonds are blocked, resulting in a lethal change in protein structure.
Sterilization processes act either chemically or physically, leading to a lethal change in the structure or function of organic macromolecules in microorganisms.
It can cause severe damage to the digestive system, and a potentially lethal change in the acidity of the blood.
We discuss three interlinked issues: the natural pace of environmental change and adaptation, the likelihood that a population will adapt to a potentially lethal change, and adaptation to elevated CO2, the prime mover of global change.
For the majority of chemical stressors tested, behavioral sub-lethal changes occurred early and in a concentration- and exposure time-dependent manner and could be recorded with no "observer" input.
To define the pre-lethal changes in circulating parameters, mice were retrospectively divided into two groups based on outcome in the acute sepsis: DEAD (all died within 5 days, n = 39) and survivors (SUR; alive at day 28, n = 40).
Does the assignment of synthetic lethals change if the dataset is made non-redundant?
